Propanamide, 3-chloro-N-[(2-fluorophenyl)methyl]-
3-Chloro-N-(2-fluorobenzyl)propanamide
CAS: 895367-68-7
Molecular Formula: C10H11ClFNO
Propanamide, 3-chloro-N-[(2-fluorophenyl)methyl]- - Names and Identifiers
| Name | 3-Chloro-N-(2-fluorobenzyl)propanamide |
| Synonyms | Albb-003568 CHEMBRDG-BB 9071390 3-Chloro-N-(2-fluorobenzyl)propanamide Propanamide, 3-chloro-N-[(2-fluorophenyl)methyl]- |
| CAS | 895367-68-7 |
Propanamide, 3-chloro-N-[(2-fluorophenyl)methyl]- - Physico-chemical Properties
| Molecular Formula | C10H11ClFNO |
| Molar Mass | 215.65 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD08076778 |
Propanamide, 3-chloro-N-[(2-fluorophenyl)methyl]- - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
Propanamide, 3-chloro-N-[(2-fluorophenyl)methyl]- - Introduction
3-Chloro-N-(2-fluorobenzyl)propanamide is a compound whose chemical formula is C10H11ClFNO. The following is a description of its nature, use, formulation and safety information:
Nature:
- 3-Chloro-N-(2-fluorobenzyl)propanamide is a colorless or slightly yellow solid.
-Its density is approximately 1.3g/cm3.
-It is non-volatile at room temperature.
-This compound has low solubility in water.
Use:
- 3-Chloro-N-(2-fluorobenzyl)propanamide is commonly used as an intermediate in organic synthesis.
-It can be used to prepare other organic compounds, such as drugs, pesticides and dyes.
-Due to its unique chemical structure, it may also have other specific application fields, such as drug research or catalytic reaction fields.
Preparation Method:
The preparation method of 3-Chloro-N-(2-fluorobenzyl)propanamide can be achieved by the following steps:
1. First, 2-fluorobenzaldehyde is reacted with chloropropionic acid in an appropriate solvent to generate 3-chloro-2-(2-fluorophenyl) propionic acid.
2. Next, 3-Chloro-N-(2-fluorobenzyl)propanamide can be obtained by condensation reaction of the above product with ammonia water.
Safety Information:
-When using and handling 3-Chloro-N-(2-fluorobenzyl)propanamide, appropriate laboratory safety procedures must be followed.
-This compound may be irritating to the skin, eyes and respiratory system.
-Wear appropriate personal protective equipment such as lab gloves, safety glasses and respiratory protective equipment when used.
-Keep away from ignition and oxidizing agents during storage and handling.
-Seek immediate medical help if exposed or unwell.
Nature:
- 3-Chloro-N-(2-fluorobenzyl)propanamide is a colorless or slightly yellow solid.
-Its density is approximately 1.3g/cm3.
-It is non-volatile at room temperature.
-This compound has low solubility in water.
Use:
- 3-Chloro-N-(2-fluorobenzyl)propanamide is commonly used as an intermediate in organic synthesis.
-It can be used to prepare other organic compounds, such as drugs, pesticides and dyes.
-Due to its unique chemical structure, it may also have other specific application fields, such as drug research or catalytic reaction fields.
Preparation Method:
The preparation method of 3-Chloro-N-(2-fluorobenzyl)propanamide can be achieved by the following steps:
1. First, 2-fluorobenzaldehyde is reacted with chloropropionic acid in an appropriate solvent to generate 3-chloro-2-(2-fluorophenyl) propionic acid.
2. Next, 3-Chloro-N-(2-fluorobenzyl)propanamide can be obtained by condensation reaction of the above product with ammonia water.
Safety Information:
-When using and handling 3-Chloro-N-(2-fluorobenzyl)propanamide, appropriate laboratory safety procedures must be followed.
-This compound may be irritating to the skin, eyes and respiratory system.
-Wear appropriate personal protective equipment such as lab gloves, safety glasses and respiratory protective equipment when used.
-Keep away from ignition and oxidizing agents during storage and handling.
-Seek immediate medical help if exposed or unwell.
Last Update：2024-04-09 21:01:54
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